Mass spec sees double

Wave-spec: a preprocessing package for mass spectrometry data

UNLABELLED Wave-spec is a pre-processing package for mass spectrometry (MS) data. The package includes several novel algorithms that overcome conventional difficulties with the pre-processing of such data. In this application note, we demonstrate step-by-step use of this package on a real-world MALDI dataset. AVAILABILITY The package can be downloaded at http://www.vicc.org/biostatistics/supp...

Spec Cpu2006

On August 24, 2006, the Standard Performance Evaluation Corporation (SPEC) announced CPU2006 [2], which replaces CPU2000. The SPEC CPU benchmarks are widely used in both industry and academia [3]. The new suite is much larger than the previous, and will exercise new corners of CPUs, memory systems, and compilers – especially C++ compilers. Where CPU2000 had only 1 benchmark in C++, the new suit...

Electron diffraction sees hydrogen atoms

Dark Matter Sees The Light

We construct a Dark Matter (DM) annihilation module that can encompass the predictions from a wide array of models built to explain the recently reported PAMELA and ATIC/PPB-BETS excesses. We present a detailed analysis of the injection spectrums for DM annihilation and quantitatively demonstrate effects that have previously not been included from the particle physics perspective. With this mod...

Guanylyl cyclase sees the light

Cyclic guanosine monophosphate (cGMP) is a critical second messenger that regulates cardiovascular function and vision in humans. Two recent papers, including one in BMC Structural Biology, have revealed atomic structures of the enzymes that catalyze the synthesis of cGMP providing new clues about the molecular basis of substrate specificity and allosteric regulation in nucleotide cyclases.